Suggestions(1)
Exact(2)
The results show that for small and moderate sample sizes calculation of the MECOSA estimators is problematic because of convergence problems and a tendency to underestimate the root mean squared errors.
The hypotheses for both studies were based on expected ORR (⩾15%), accordingly the sample sizes (calculation using SAS version 8.2, UNIX/Solaris) ensured ⩾74% power to deem lapatinib monotherapy effective by correctly rejecting the null hypothesis (H0: P<0.05) and accepting the alternative hypothesis (H1: P>0.15).
Similar(58)
Fig. 1 Sample size calculation.
Sample size calculation was performed.
Therefore, sample size calculation was not performed.
RCTs reported the sample size calculation.
Sample size calculation.
Sample size calculation is needed.
No sample size calculation has been performed.
See Supplemental Material for "Sample size calculation".
Two studies reported a sample size calculation.
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