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Such a situation might be appropriate where a measure is poor at discriminating between individuals within the normal range but can reliably detect sizeable impairments in social functioning.
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Although, compared to the past generations, the second generation antipsychotics have shown different side effects, shortly after consuming drugs as Clozapine and Olanzapine, some undesirable effects ranging from sizeable weight gain and lipid/glucose impairments to serious but rare side effects such as priapism broke out through the course of treatment [ 1].
A recent meta-analysis of injury severity, functional impairment, and outcomes after TBI found that functional impairment (as measured by the FIM) had sizeable effect sizes in relation to "global disability," but very low effect sizes were found between FIM scores and various measures of quality of life [ 1].
However, patients with renal impairment do account for a sizeable portion of ICU clientele, and it is incongruous to attempt the establishment of guidelines for the use of LMWH prophylaxis in ICU patients, whilst continuing to exclude this important subgroup.
Despite the sizeable cohort recruited, the study was powered to detect a difference in cognitive impairment between two groups (LMPT vs term).
However, with sizeable and widely varying proportions of patients experiencing recurrent low back and leg pain or other impairment post-operatively, optimising the outcome of spinal surgery appears to be a priority for further research.
Specific language impairment (SLI) and developmental dyslexia (henceforth, dyslexia) are developmental disorders of communication that affect a sizeable proportion (∼7 10%) of the school-aged population (Tomblin et al., 1997; Snowling, 2000).
The "if", though, is sizeable.
The cost is sizeable too.
This list is pretty sizeable.
"That is a sizeable risk.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com