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The absence of sizeable effects in CA3 accords with prior reports showing that colchicine-induced destruction of the granule cells does not severely affect theta activity [37] or the activity of CA3 place cells [38].
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We conclude that these effects were largely treatment-associated and will not exert a sizeable effect in newly diagnosed, untreated patients.
Based on analysis of the crystal structures, we show that specific substitutions at the 4-position of the azabicyclo[5.3.0]alkane scaffold results in sizeable effects on the peptidomimetic BIR3 domain affinity.
A recent meta-analysis of injury severity, functional impairment, and outcomes after TBI found that functional impairment (as measured by the FIM) had sizeable effect sizes in relation to "global disability," but very low effect sizes were found between FIM scores and various measures of quality of life [ 1].
Male adult feeding, in contrast, had sizeable effects on almost all aspects of male and female reproduction, through the nutritional effects of ejaculates in females.
The Vespoidea (excluding Sierolomorphidae) and the Anthophila + Sphecidae (forming the majority of Apoidea) are also recovered as significant positive shifts in diversification with possibly sizeable effects on species richness (Table 1).
In any case, these sizeable effects of both earthworms and AMF on these invasive slugs adds further evidence for belowground control of plant community structure via modifying aboveground herbivore behavior.
Changes in the core parameters have relatively small influences in total energy absorption but sizeable effects on the force-displacement curve and failure modes.
In summary, mtDNA variation had sizeable effects on adult longevity but these effects were contingent upon the nuDNA background and were generally stronger in females compared to males.
They find sizeable effects on reading skills and weak evidence of a reduction in grade retention.
However, non-randomised data supporting sizeable effects of RDN on office and ABPM parameters have now been published in a study of 346 patients with true RHTN (n=303) and pseudoresistant HTN (n=43).
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