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Processing and polyadenylation is mediated by a sizeable complex of factors [2]; this complex recognizes specific sequence elements in the pre-mRNA, cleaves the pre-mRNA at a particular site, and facilitates the addition, by poly(A) polymerase, of the poly(A) tract to the cleaved pre-mRNA.
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By that time, according to the Senate report, Dimon "was already in possession of information about the [London Whale's] complex and sizeable portfolio, its sustained losses for three straight months, the exponential increase in those losses during March, and the difficulty of exiting the [London Whale's] positions".
There was also a sizeable effect of more complex and sexually non-reciprocal genetic interactions (σ k ) in F1 productivity.
That fact became evident by sizeable discrepancies in muscle-tendon complex length between the groups.
Urban management is a complex process, which requires a sizeable information base and a large coordination between the actors who are managing the city.
The invitation and its acceptance surprised the Obama administration, and a sizeable chunk of the Washington political-media complex flew off the handle in response, working itself into an epic tizzy.
The legacy of the crisis is too intricate and complex to be easily solved, and sizeable challenges for the Spanish economy remain.
The Five Star Movement, another newcomer which appeals to voters fed up with all political parties (see article) will also get a sizeable vote.Things are made more uncertain by a crazily complex electoral system.
Bridgespan has since chalked up a sizeable list of successes in the US "social services-industrial complex", which was worth $1.87tn in revenues and $4.30tn in assets in 2009, according to the National Centre for Charitable Statistics.
Complex middle cerebral artery aneurysms include aneurysms that are sizeable (large or giant), broad-necked, fusiform, dissecting or serpentine; many of these types of aneurysms cannot be treated with direct aneurysm neck clipping or dome coiling.
Both tumour types are relatively common and include a sizeable proportion with advanced or metastatic disease, which in some cases require complex treatment decision-making.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com