Sentence examples for sizeable burden from inspiring English sources

Such a restricted system would put a sizeable burden on state and local authorities, without ample support from the users themselves.

The hypothesis at the start of this research was that ADPKD patients, even early in disease, would pose a sizeable burden to the US health care system.

The largest disparity by Indigenous status was observed for frequency of blood glucose and lipid measurements which is perhaps of even greater concern due to the sizeable burden of diabetes and cardiovascular disease among Indigenous Australians [ 7].

Indeed, the costs of dialysis and renal transplantation imposed by ESRD implicate a sizeable burden on health care resources [ 3] and seriously compromise both the quality of life and life expectancy [ 4- 7].

3 The sizeable burden of behavioural problems over the lifespan is suggested by their early age of onset, 4 stability over time 5 6 and increased risk of onset of other psychiatric disorders throughout childhood, adolescence and adulthood, including conduct disorder (for ODD), 7 depression 8 and substance abuse.

There is a perception that the disease burden of ADPKD during the early stages of the disease, when kidney function is still classified as normal (glomerular filtration rate [GFR] ≥60 mL/min/1.73 m), does not place a sizeable burden on medical resource utilization (MRU).

We did not measure the rate of muscle protein breakdown (MPB) (which was unwarranted without more indicative data of possible sex differences given the already sizeable investigational burden on our subjects).

Besides a nuisance problem causing vaginal discomfort [ 10], BV is also associated with a sizeable disease burden [ 11].

Despite the limitations, the estimates reported in this paper demonstrate that maternal mortality imposes a sizeable economic burden on African Region countries.

18 Recent studies have identified Indonesia's sizeable chronic disease burden but little is known regarding the pattern of multimorbidity in the population.

There is a sizeable and growing burden of drug-resistant TB in China, and this has implications for the management of DM patients.