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Although it has been known that a risk of thromboembolism increases when the size of vegetation exceeds 10 mm, this size criteria should apply to the case with vegetation associated with infective endocarditis.
However, due to the fact that the in-hospital mortality rate for infective endocarditis (IE) is 18% and that there is a direct correlation between size of vegetation and mortality [46], it is important to keep this in mind when an irregular cardiac mass is identified with FocUS.
Further, in right-sided endocarditis in drug users, size of vegetation >2 cm proved a major prognostic factor of in-hospital mortality [ 26].
Including more vegetation types would be difficult since the limited range and dynamics of NDVI-FR and size of vegetation patches within the High Arctic are limiting factors for the number of vegetation types that can be explored [ 44].
Moreover, in the present case, the antibiotic therapy alone was only able to suppress circulating bacteremia, but failed to decrease the size of vegetation and the nest of bacteria.
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There is a strong correlation between the size of vegetations seen on MSCT and echocardiography [7].
3) The size of vegetations is small (These vegetations have been imaged successfully with other tracers: 99mTc-AnnexinV with a ratio of 1.3 for in vivo acquisitions and 2 for autoradiography (Rouzet et al. 2008); Annexin A5-128 with similar diagnostic sensitivity than Annexin V (Benali et al. 2014)).
* Size of vegetations measured in 598 patients.
Third, as TEE was not systematically performed, evaluation of echocardiographic data (size of vegetations, perivalvular extension) may be biased.
In our study, a vegetation size of >20 mm almost reached statistical significance in univariate analysis but did not in multivariate analysis; a limitation of our study is that size of vegetations was not measured in all cases.
It must be enlighten that some well identified predictors of poor prognosis such as some echocardiographic findings (size of vegetations, presence of periannular complications, severity of valve dysfunction at diagnosis) and the presence of foreign material [ 2, 18, 23- 25] couldn't be deduced from HDR.
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