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However, the size of the pathways identified by them could be very small, sometimes with only two genes.
In the permutation tests the enrichment scores were properly normalized in order to consider the size of the pathways.
Further, the performance of NBF improves with increasing pathway size, whereas that of SNAL is unaffected by the size of the pathways.
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Furthermore, the size of the pathway from the reservoir may be considerably smaller and invisible at frequencies equal to or lower than 16 Hz.
The other key number to look at is that of the front-side bus, referring to the size of the pathway between the processor and the PC's main memory.
Had the size of the pathway been a prominent factor, more overlap would be expected.
To reduce the number of optimal solutions the size of the pathway is also minimised.
The measured values were divided by the size of the pathway [ 14].
In this regard, a relationship may exist between the discriminative ability of a pathway expression profile and the size of the pathway, since the size of a pathway may indicate either complexity or extent of characterization of the pathway.
From a statistical point of view, inference results could be affected by the size of the pathway.
We also found a correlation between the number of protein hubs and the size of the pathway (the Pearson correlation coefficient is 0.79 at P-value <2.2 × 10−16).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com