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FreedomPop's user base of one-quarter of a million subscribers is tiny compared to the size of carriers like Verizon Wireless, which has nearly 125 million subscribers.
Accessibility limitations are more stringent for carriers relying on multivalent binding and are proportional to the size of carriers.
While other genes had a significant interaction effect (e.g. cluster I in Fig. 3), we cannot exclude the possibility that our ability to detect this interaction was limited by the sample size of carriers.
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"I am not famous anymore" ran the slogan, doubtless painstakingly scrawled by some luckless flunky who'd spent an age sourcing the right size of carrier, snipping out the eyeholes, trying to spray out the smell of sausages.
However, since the ratio of the size of carrier to that of APIs for carrier-based formulations is normally larger than 10, even up to 20, it is challenging to determine the localised air flow at the API size level using DEM CFD, as the fluid cell size employed in DEM CFD is relatively large (i.e., >the carrier size).
It seems unlikely that the size of ore carriers will reach anything like the dimensions already attained by supertankers.
We conclude that the size of antigen carriers plays a critical role in directing antigen to the class I antigen presentation pathway.
Although particle size has been recognized as a critical factor of vaccine design, it is unclear how the size of vaccine carriers impacts the intracellular processing of exogenous antigen and cross-presentation onto MHC class I molecules.
The biggest ships are now the size of aircraft carriers, ferrying thousands of passengers and crew from port to port.
For example "… specific proteins may control the loading of big cargoes and regulate the size of COPII carriers accordingly… Recent findings have revealed that the proteins TANGO1 and cTAGE5 assemble into a dimer at the ER exit sites and that both are required for Collagen VII secretion.
Sedlin, a gene implicated in spondyloepiphyseal dysplasia tarda (Christie et al., 2001; Matsui et al., 2001; Mumm et al., 2000) that is characterised by altered extracellular matrix production, could modulate the size of nascent carriers by regulating Sar1A-mediated COPII coat dynamics for procollagen export from the ER (Venditti et al., 2012).
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