Your English writing platform
Discover LudwigExact(3)
This is a size of binding pocket that is within reach of what are commonly considered drug-like molecules (Lipinski, 2004).
We assigned binding nucleotides a weight of 1.3 to balance the data size of binding nucleotides with that of non-binding nucleotides.
We also assessed disease/trait overlap using the central 200 bases of each binding site to control for differing size of binding sites and found very similar results (Additional file 1: Table S6).
Similar(56)
Intuitively, one could predict that these proteins might also bind smaller substances due to the size of their binding pocket (while not binding larger molecules than the one they are tuned to).
The fitness of an individual, f, is defined as with l the length of bite, g the genome size (number of binding sites and genes), pen the genome size penalty coefficient, and σ the selection coefficient.
We use a small value h′ = 20, motivated by the size of miRNA binding sites or protein binding motifs [Bahadur et al., 2008].
The derived analytical model takes into account the adsorbate molecule size, distribution of binding sites as determined by the crystallographic structure of the sensor surface and multi-site adsorption.
Unfortunately, attempts to construct accurate binding site predictors have been frustrated by the small size of the binding sites, which means that DNA regions identical to functional binding sites occur by chance with high frequency.
The protein ligand complexes can also yield information about all interactions that ligands could potentially form with the binding site, as well as about the size of the binding cavity.
In addition, we considered the size of the binding site.
The size of the binding site was 28 × 40 × 24 Å.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com