Sentence examples for size of alterations from inspiring English sources
This approach avoids missing important genetic changes between BACs but, by definition, overestimates the size of alterations.
Comparison of continuous variables (number and size of alterations between different tumour groups and clusters) was done using Student's two-tailed t-test (for variables of normal distribution) or the Mann–Whitney test (non-parametric distributions).
To predict the size of alteration that could reliably be detected, given a fixed number of computationally sampled tags, we used Monte Carlo simulation to calculate a positive predictive value (PPV), which is the probability that a detected alteration represents a true alteration.
The genome-wide CNV rate was quantified by determining the cumulative size of genomic alterations (bp) in genomic regions that harboured a copy number change of <−0.3 (for loss) or >0.3 (for gain).
For the SNP 6.0 array, this bias towards gains was more important as the size of the alterations decreased, but only for VOUS (see Figure 2).
While the size of these alterations makes them immaterial to the analysis in this paper, it should be borne in mind that 1) the numbers in Tables 1 and 2 are not an exact representation of the full census results and 2) a separately-prepared custom extract of precisely the same variables from the same census may yield slightly different numbers.
The size of hydrothermal alteration zones can range from millimeters to several kilometers.
Signs of immunosuppression were most evident in septic shock, regarding both the number of patients and the size of the alteration.
The ability of DGS to detect genome-wide changes is based on genome characteristics, such as the copy number and the size of the alteration, and the number of real tags obtained from sequence analysis.
Each quantitated copy-number change as determined from quantitative real-time PCR (qPCR) of genomic DNA was remarkably similar to that estimated by DGS when the window size for tag density analysis was matched to the size of each alteration (Additional file 9a-d).
The locations and sizes of the alterations are summarised in Figure 1.
