A sample size objectives of 600 subjects was estimated to provide a power of 88.35% to evaluate each of the co-primary objectives.
All such studies present a quite variable picture of the disease depending on the factors focused like sample size, objectives of study, associated risk factors, population under study, diagnostic assays practiced, ethnicity, socio-economic status and general population behavior.
The study includes a relatively large sample size, objective measurements of albumin leakage and the use of validated headache diagnoses.
The study includes a relatively large sample size, objective measurements of UAE, analyses based on fresh urine samples and the use of validated headache diagnoses.
The strengths of our study are its size, objective assessment of proximity to powerlines and freedom from any obvious source of bias.
Shin et al's RCT [ 50] is excellent quality with double-blinding, powered sample size, objective and subjective outcomes and good reporting.
The SEYLE project achieved the sampling size objective of enrolling at least 1,000 participating pupils at each site (except Austria; n=960), for a total sample of N=12,395 school-based adolescents.
Due to the methodological approach of a pilot study, including a limited sample size, objective benefits of routine HRQoL assessment, as well as generalisability of the participants' statements, need to be confirmed within a larger controlled study.
The main strengths of our study include its population-based nature, inclusion of a representative multiethnic sample, adequate sample size, objective measurement of diabetes status following current guidelines, and the availability of extensive data on confounders for multivariate adjustment.
In this community-based prospective study, the strengths were a relatively large sample size, objective measures of individual exposure based on urinary arsenic concentrations twice during pregnancy, prospectively collected outcome data, and availability of data on important covariates to adjust for possible confounding.
Our sample size objective was to include approximately 385 individuals from each of the 4 largest groups of immigrants in the city (Latin America, Maghreb, sub-Saharan Africa and Eastern Europe), in order to estimate proportions by zone of origin with a sampling error of 0.05 or lower.
