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A sample size calculator is presented for calculating appropriate sample sizes for cluster trials, whilst allowing the implications of both methods of inflation to be considered.
In order to compare the relative efficacy or effectiveness of the studies, between group effect sizes were estimated using an effect size calculator [ 45] to calculate Cohen's d[ 46] at post-test and follow-up where provided.
A sample size calculation was performed with a sample size calculator by Rasoft, Inc. http://www.raosoft.com/samplesize.html.html
The Stata version 10.0 sample size calculator has been used to calculate the target sample size.
The sample size was calculated using the sample size calculator available online.
Effect sizes and 95% confidence intervals were calculated using the Effect Size Calculator from the Centre for Evaluation and Monitoring, Durham University http://www.cemcentre.org/.org/
The minimum required sample size was calculated using electronic sample size calculator (with 5% margin of error, 95% confidence level and 50% response distribution); and it was found to be 400 including 10% non-response rate).
To detect a "moderate" effect size (0.6) at 80% power and 5% level of significance (2 tailed distribution), the required sample size for each group (intervention and control) is 27 physiotherapists (calculated using standard sample size calculator software in MedCalc).
Sample size was calculated using a Raosoft sample size calculator.
Power calculations performed with the Sample Size Calculator (Schoenfeld, 1983).
Sample size for in vitro/in vivo experiments was calculated by means of Sample Size Calculator (http://www.stat.ubc.ca/~rollin/stats/ssize/index.html; parameters: power,.80; alpha,.05).
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