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Four previous studies reported that primary ICD implantation in routine clinical practice was associated with a sizable survival benefit comparable with those seen in major trials, 39 47 48 49 but only one 39 included the subset of elderly patients who underwent device implantation during an acute hospital admission.
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The consistent application of the KC differential survival did not display sizable differences between the pre- and post-test (21.4 vs. 22.2%, respectively).
Trials have demonstrated improvements in survival and symptoms after TAVR versus medical therapy; however, there remains a sizable group of patients who die or lack improvement in quality of life soon after TAVR.
10 11 12 Notwithstanding, none of the randomised trials has been adequately powered to deal with survival, whereas treatment effects were reduced owing to crossover to revascularisation in a sizable proportion of patients and exclusion of high risk patients based on angiographically defined extent of coronary artery disease.
Although the carryover effect was greater than density-mediated compensation, this compensation was substantial enough to offset a sizable portion of the carryover effect, resulting in a nonsignificant relationship between exposure concentration and net postexposure survival (F1,40 = 3.55, p = 0.067; Figure 2C).
First, in spite of the fact that use of advanced technologies, especially in the design and engineering sphere, favors survival, remarkable differences do emerge between different individual technologies; ceteris paribus, plants having adopted technologies characterized by sizable, product-specific investments turn out to be less likely to be shut down.
Even with ATRA/ATO treatment, a sizable portion of high-risk patients (17.6% in this study) still experienced difficult induction intercourse, disease recurrence and short survival.
Survival was markedly increased (73%) among infants between 1.5 and 2.5 kg, with this group making up a sizable proportion of all NICU admissions (33%).
And these are sizable.
But they are sizable.
That's a sizable victory.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com