Sentence examples for sizable substitution from inspiring English sources

This sizable substitution of new drugs for traditional ones shows the potential of a generous health care system in providing better access to new drugs for their beneficiaries by encouraging the adoption and use of expensive medical technology.

These are healthy substitution strategies.

Analysis of >2800 Co-hArgI variants revealed a sizable number of amino acid substitutions in second-shell residues that confer appreciable catalytic activity at physiological pH, a few even resulting in a higher kcat/ Km relative to that of the parental enzyme.

This behavior is illustrated in Figure 7. aFor completeness, we mention that in the presence of sizable fractional blood volume (fbv), the substitutions K m → K m ∗ = ( 1 - fbv ) K m and V r → V r ∗ = ( 1 - fbv ) V r + fbv = V r + fbv ( 1 - V r ) would have to be performed in Equation 5 where the 'asterisked' quantities would be the experimentally accessible ones.

At pH 5 5 epi formed about 10 times faster than its presumed C15-epimer (named iso -5 epi, see below), pointing to a sizable stereoselectivity in the indicated acid catalyzed substitution at C15 of a hydroxyl group by a methoxy group.

Here, we carried out the first comparative study of substitution rates and mutational patterns in a sizable fraction of the conifer gene set - or that of any gymnosperm.

They have found either no sizable effect of immigration on natives or a very small positive effect on natives, suggesting that there may be limited substitution between immigrants and natives in immigrant-receiving metropolitan areas (Altonji and Card 1991; Butcher and Card 1991; LaLonde and Topel 1991; Shoeni 1997; Card 2005).

And these are sizable.

But they are sizable.

Does the substitution matter?

80 min: England substitution.