Initially, duplications generate functional redundancy, a situation that is generally non-advantageous; hence, even if duplicates have been fixed by chance, the accumulation of mutations will result in the disruption of structure and function of one of the duplicates, which becomes a pseudogene (i.e. a non-functional gene).
Mr. Vallone, the City Council speaker and the candidate whose campaign has, to a large extent, been directed at the elderly and middle class white and black residents in boroughs outside Manhattan, is buying heavily in situation comedies that generally appeal to an older, more middle class audience.
They generally lacked protective equipment – a situation that is a clear manifestation of the extent of poverty in the neighbourhood.
As mentioned earlier, there appears to be no universally compelling reason to use one test over the other, as theoretical results are limited to specific situations that are not generally applicable.
That generally makes things worse.
"That generally stops them".
His reputation for not finishing things meant that he no longer received big commissions, a situation that he generally felt as a relief, except when confronted with the galling achievements of Michelangelo and Raphael, in their positions as favorites of the Pope.
It's true that social norms are sometimes less restrictive in some ways for poor people in some situations, but that's generally a function of peer expectations, not of state surveillance.
Previously, the immigration service could set aside judges' rulings only in cases of clear-cut criminal activity, situations that are unusual because judges generally impose high or no bail in such cases.
