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Similar to the in vivo situation, expression of P1c was maintained when cultured keratinocyte monolayers were induced to stratify and undergo terminal differentiation, whereas expression of P1a was down-regulated (Kostan et al. 2009).
In conclusion, it seems that considering our limited understanding of biology, and the current research funding situation, expression profiling stands out as the most appropriate and cost-effective methodology to gain new insights into complex disorders and to discover disease and drug-response biomarkers.
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To take into account the intrinsic random character of the phenomena in practical situations, expressions for the probability of exceeding the condition for successful flight under short duration gusts are obtained, assuming common probability density functions for the random parameters involved.
In this situation, reporter expression pattern induced by CNE-enhancer was compared manually (via images) with the reported endogenous expression pattern of candidate neighboring genes.
In the normal situation the expression of HSP47 precedes that of collagen, and in various cell types and tissues the co-expression of the proteins is present (26).
This is clearly not the observed situation when expression data from various cnidarian taxa are compared.
For instance, if the nutritional situation requires expression of gene A, how do cells switch into the attrator state in which A is stably expressed?
In this hypothetical situation, the expression of MarT in S. Typhi could have unexpected effects on several pathogenic associated phenotypes, probably decreasing the virulence of this human restricted serovar.
In this situation, the expression of basic reproduction number R0 is given in Section 4.1.
In a reverse situation, its expression level may be considered relatively low.
In this situation, reduced expression of PHLDA2 could have had a selective advantage through greater placental development.
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