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In such a situation, alignment-dependent approaches may produce ambiguous results or fail completely.
In such a situation, our alignment approach will correctly align to and to since, for pairwise alignment, our algorithm returns a chain of fragments with maximum total score.
In this situation, local alignment is not attempted because the global alignment is sufficient, and thus there is no soft-clipping done.
To me, play-by-play is describing all the events occurring on the field: ball-and-strike count, pitch to the batter and what occurs, runners on base and the score situation, defensive alignment, some personal player notes and an occasional stat, culminating with the base hit, runners racing, sliding, scoring.
We then characterize the different situations of alignment between business and technology, for different models set in our modeling framework, taking into account standard business knowledge and applications.
In many situations, the alignment needs not match between every point in the two sequences.
In addition, we have applied the exposure filter to the recently published proteasome data as suggested by the reviewers, and we also tested its performance in a situation where the alignment accuracy is significantly limited by the strength of the signal present in the images.
It locally produces pressure oscillations in the vicinity of shocks and in cases of adverse grid situations and flow alignment.
Alignment situations are believed to be a source of circular polarization in molecular clouds, where high levels of circular polarization (~10% or more) have been measured (Bailey et al., 1998; Chrysostomou et al., 2000; Menard et al., 1999).
There are many situations where automated alignment procedures can produce biologically incorrect aligments.
We illustrate the advantages of CodonLogo in comparison to sequence logos in Figure 1. Figure 1A shows an artificial situation, where two alignments are compared.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com