Sentence examples for situ immunity from inspiring English sources

Human TRMs in diverse sites exhibit increased expression of adhesion and inhibitory molecules, produce both pro-inflammatory and regulatory cytokines, and have reduced turnover compared with circulating TEM, suggesting unique adaptations for in situ immunity.

The effects of the host immune response on tumour cell proliferation, survival, invasion, recurrence and metastasis are demonstrated by an analysis of in situ immunity.

As an alternative approach to targeted vaccination, non-surgical tumor ablation such as cryoablation induces anti-tumor immunity via in situ immunization, particularly when combined with toll-like receptor (TLR) agonist.

T1R have been characterized by in situ Th1 type immunity with spontaneous increase in cell mediated immunity with infiltration of IFNγ and TNFα, secreting CD4+T cells in skin lesions and nerves.

Recent studies suggest that radiotherapy can be applied as a powerful adjuvant to immunotherapy, and can even contribute to converting the irradiated tumour into an in situ vaccine, resulting in specific immunity against metastases [1].

Further, the self-limiting nature of C. jejuni-mediated gastroenteritis in the majority with few requiring hospitalisation, and the added risk of intestinal perforation severely curtails the opportunity to investigate immunity to infection in situ.

In summary, our results show that targeting HER2 protein to activated DCs in situ significantly enhances anti-tumor T-cell immunity, and we propose that this strategy provides a feasible approach for immunotherapy in patients with cancer.

The potential of this local in situ T cell re-stimulation to induce a systemic anti-tumor immunity is discussed.

The human gut microbiota has been shaped by the long co-evolutionary history of symbiotic host-microbe interaction [1] and has evolved to play an important role in maintaining human health by preventing colonization by pathogens, degrading dietary and in situ-produced compounds, producing nutrients, and shaping and maintaining the normal mucosal immunity [2] [4].

Our in situ analysis provided evidence that anti-angiogenic treatment reprogrammed the immune contexture of M/DSFTs and favoured the onset of an active T-cell immunity.

The cDNA expression patterns determined by in situ hybridization indicated that the CAG25409 protein has a role in body pattern formation and immunity.