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Cla4 phosphorylates Cdc24 in this complex likely at multiple sites; the function is not clear, but one study has suggested that this phosphorylation negatively regulates Cdc24 function [12], [17].
On some sites, the plantation crop eventually grows through the weeds, dominates the site, and becomes established; on such sites, the function of weeding is to increase crop uniformity and speed up the process of establishment and growth.
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The exact phosphorylation sites and the function of Plk1-mediated proteasome regulation in mitosis remain to be determined.
It also elucidated the relative importance of these sites in the function of the enzyme.
In essence, binding of a ligand at an allosteric site affects the function at a distant site exploiting protein flexibility and reshaping protein energy landscape.
The N-terminal domain contains the bifunctional active site, but the function of the C-terminal domain is unknown.
A feedback mechanism was proposed to explain how the CuA site regulated the function of cytochrome c oxidase.
The Ku protein complex is then recruited to the damaged site with the function of protecting the DSBs from further degradation.
They react with a serine residue at the catalytic site, thus disabling the function of AChE.
Predictably, mutations in site 219 disrupt the function of the protein [ 40].
While users may be skeptical of handing over their LinkedIn password to one of these sites, the hash algorithm function converts the password into a series of characters.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com