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Sites of response were similar in both groups.
The sites of response were lung and lymph nodes for both patients.
Sites of response included soft tissue/nodal (three patients) and lung (one patient).
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These bioresponsive nanosystems present several unique features such as no need of an external device, precision control over site of response (from tumor tissue down to cellular organelle level) following accumulation in the tumor via either passive or active targeting, and spontaneous activation in the tumor site or inside the tumor cells.
It is noteworthy that these models all include some action at the plasma membrane, which is also the suggested site of response to cold stress.
aFrom left to right are fields for responder or site of response, site address, date of pick-up, date of intake, bag contents, location of testing, comments, priority, swab taken (yes, no), and patient (if clinical sample).
When stratified according to site of response, 11 (31%) patients had a partial response at sites of extraovarian metastases and only five (14%) had a partial response in the ovaries.
Interestingly, methylation associated SNP clusters were over-represented near the transcriptional initiation sites of immune response genes.
With application of kinetic modeling of [18F]-FDG uptake in infected animals, researchers will be able to pinpoint sites of immune response and quantify anti-inflammatory effects of potential antiviral treatments.
Thus, another possibility is that the activated CD8 T cell fate may also vary with different routes of infection and/or at different tissue sites of immune response.
Potential binding sites of the response regulator MbrC were deleted using a PCR-driven overlap extension method [ 120].
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