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Other sites of physiological FDG activity can be confused with malignancy.
Keratinocytes are one of the few sites of physiological Brk expression [ 20, 21], however, Brk's role in these cells has yet to be fully characterized.
Data sets were reviewed for frequently affected chromosomal sites of physiological copy number variations (CNV), using comparison with the genomic variants database (http://projects.tcag.ca/variation/).tcag.ca/variation/
Furthermore, myosin light chain kinase a key regulator of the actomyosin purse-string contraction wound closure mechanism in epithelial lining has been observed at the sites of physiological and pathological cell shedding.
In this species the koniocellular layer K3 is sandwiched between the main magnocellular and parvocellular layers of the LGN and is broad enough (Kaas et al., 1978; Spatz, 1978) to make histological reconstruction of the sites of physiological recordings relatively straightforward.
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The gastrointestinal tract is a common site of physiological and incidental FDG uptake [ 12- 23].
However, these mechanisms and the actual site of physiological regulation of physical activity at this point are somewhat unclear.
Given that the early corpus luteum is already the most active site of physiological angiogenesis in the adult (1), the resultant increase in endothelial proliferation after neutralization of Dll4 is remarkable.
This notwithstanding, it should be pointed out that the expression level of SPINK1, as well as that of the digestive enzymes in the COLO-357 cells, is certainly much lower than that in their principal site of physiological expression, human pancreatic acinar cells.
This space is the usual site of physiological function of this neurotransmitter and other neurotransmitters as well.
Besides, other peptides substrates of furin derived from the processing site of its physiological proproteins can be employed to validate this new hypothesis of ours for protease inhibitor design.
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