Sentence examples for sites altering from inspiring English sources

Additionally, HNE modifies proteins at exposed nucleophilic sites, altering tertiary structure and ultimately modifying activity.

SRPKs phosphorylate RS domains at numerous sites altering SR protein subcellular localization and splicing function.

There are also occurrences of 5' and 3' alternative splice sites altering the length of some exons.

Additionally, mutations in existing introns may engender compensatory mutations or activation of latent splice sites altering the lengths of associated intronic and exonic sequences (Gan et al. 2011; Long et al. 2013).

How do ratings and review sites alter the relationship between businesses and consumers?

A simple explanation of this result is that changes at the +4 and +5 sites alter the amino acid, whereas those at the +6 site may not.

Such exons may have originated from old repeated sequences, with splicing sites altered by mutation, and gained functions with time, and eventually became more frequently spliced.

Some polymorphic sites alter amino acids or lie in other functional regions; these can cause functional changes in the enzyme and result in different phenotypes [11], [13] [20].

To determine whether predicted amino acid substitutions in neutralizing antigenic sites altered the aVDPVs antigenically, thereby affecting the population immunity against them, we compared antibody titers from standard neutralization assays.

An important priority for future work will be to examine the spectrum and range of "off-target" sites altered by OPEN ZFNs, perhaps using methods previously described by other groups [27], [28].

Alterations of the charge, polarity, and size of amino acid side chains at these sites alter the ability of different divalent cations to activate the channel.