For this study, we consider case study as a research strategy, aligned with the position held by Yin [ 5, 11], as given the nature of this nationwide evaluation, the large membership of the research team and multiple case sites, a structured rather than a reflective approach to data collection and analysis was required.
Note that the previous study of Martinez suggested the present configuration L as the ground state structure (first low energy state), in which the O2 layer protons point toward the O1 oxygen site; a structure close to configuration I represented their first excited state.
Determining the occurrence and location of active and binding sites within a structure helps achieve this goal.
Because minerals are formed from a soup of different ions, it is quite common for cation sites in a structure to be occupied by more than one type of cation, frequently by several.
The observed alterations in the kinase active site generated a structure with an inaccessible electronegative active site that is catalytically inert and can serve as a stable platform for the recruitment of interaction partners [19].
We reviewed the published literature and selected plans and scaling-up proposals, interviewed experts and collected data on staffing patterns at existing treatment sites through a structured survey and site visits.
But if engineers can quickly clear debris and secure an underground retaining wall at the trade center site -- a structure often called the bathtub, since it keeps the waters of the Hudson out -- then the existing, damaged PATH station could be reopened about two years from now, Mr. Morrison said.
"To start, you have to have a site or a structure that's at least 50 years old, but you can't just go the New Jersey Historic Preservation Commission in Trenton and say, 'I have an old house, put me on the list, " he said.
Site-specific mutations are often used in LRET or FRET to direct the addition of one label to a certain site in a structure by moving the location of one cysteine.
Many riboswitches, for example, down-regulate translation by sequestering the ribosome binding site in a structure that blocks interaction with the 16S rRNA [ 63].
