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To thoroughly explore how domain engagement influences SFK ATP-binding sites, a method for sensing ATP-binding site conformation is required.
Among these, the authors found McrBc fragmentation to have the highest potential for improvement, and modified it to achieve more precise mapping of methylated CpG sites, a method they called comprehensive high-throughput arrays for relative methylation (CHARM).
It is easy to see that by starting out with a more restricted set of candidate target sites, a method can achieve a higher true-positive rate for identifying positive target sites within this restrictive set.
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At Shambhala in British Columbia, ANKORS offers reagent testing to attendees on-site, a method that uses chemical reactions to determine what a sample of a substance is.
More commonly, SNP discovery employs the sequence of the read beyond the restriction site, a method that requires higher coverage, but is more productive because it queries more sequence (currently 100 bases vs the 4 of a restriction site) and can provide codominant information for any SNP discovered.
Adherence rates from product count and self-report were fed back to sites as a method of monitoring site performance.
Agreed by most major internet service providers, final details of the scheme are still to be confirmed but it will enforce a Copyright Alert System to warn those people sharing copyrighted content using BitTorrent sites - a method of obtaining files by downloading from many users at the same time - to stop.
This is a cool move for Flipboard, and is likely a test run to observe whether users enjoy destination sites as a method of interacting with content in the app.
In contrast to prevailing calling context profilers, our tool is able to distinguish between multiple call sites in a method and supports selective profiling of (the dynamic extent of) certain methods.
A variety of computational methods have attempted to exploit the evolutionary stability of functional regions by identifying ligand binding sites as a method to predict function [4], [5].
HMMSplicer's approach allows discrimination of closely spaced alternative splice sites, providing a method to study fundamental questions about the biology of splicing which have not yet been addressed with RNA-Seq experiments.
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