This theory is widely known as "chemoattraction" theory which is similar with Paget's original paper looking at the site specific pattern of breast cancer metastases proposing "seed and soil theory" [ 38].
Given such variability, we were interested to determine (i) what fraction of positively selected genes, if any, exhibited body-site specific patterns of gene expression during invasive disease, and (ii) if the intensity of selection might depend on their putative cellular role, as defined by level of gene expression.
These results show that site properties, such as slope, aspect, and elevation, affect the thermal and hydric conditions in the soil seed bank and can cause site-specific patterns of wild oat emergence.
Protein structure mediates site-specific patterns of sequence divergence.
We would like to ask the authors to show whether GPS can predict site-specific patterns of postoperative infectious complications in SSIs and remote infections.
However, the authors did not evaluate measurable preoperative clinical and laboratory markers that may be able to predict site-specific patterns of postoperative infectious complications in SSIs and remote infections.
In our previous study, we determined site-specific patterns of risk factors for incisional and organ/space SSIs in 285 colorectal cancer patients to develop predictive models using inflammatory mediators (Miki et al, 2006).
Here, we harnessed next-generation sequencing technology in order to characterize the American pika transcriptome and identify a large suite of single nucleotide polymorphisms (SNPs), which can be used to elucidate elevation- and site-specific patterns of sequence variation.
We used them in the past in a structure-based model of evolution that predicts successfully the site-specific patterns of amino acid replacement but fails to account for the evolutionary rate variation among sites [ 44– 44].
It is important to identify which clinical and laboratory factors can predict site-specific patterns of infectious complications in SSIs and remote infections, because it may assist surgeons with specific strategies for prevention of infection according to each patient's risk factor.
