Sentence examples for site progression from inspiring English sources

Disentangling the study methodology of a priori study period, in which implementation strategies would be applied, from the overarching conceptual basis of this study (site progression through EPIS) was an inherent challenge and contribution of the JJ-TRIALS project.

Developing objective markers of the transition between EPIS stages rather than relying on assumptions about how long each stage should last (e.g., conflating study timeline with site progression toward sustainment) was one of the major methodological issues that had to be resolved in applying and rigorously testing the EPIS framework.

Although a significant increase in local control was found, the distant site progression free survival was significantly decreased after surgery.

PFS is a composite endpoint, including the appearance of "new" lesions (i.e., newly detected metastases, in a new or pre-existing metastatic site), progression of existing metastases (i.e., those present at baseline), mixed responses with some lesions increasing in size but others decreasing in size, and death.

In 12 patients (75%) the liver, either alone (N=10) or in combination with the lungs (N=2), was the initial site of progression; 3 patients (19%) progressed initially at the lungs, one of them eventually had hepatic disease progression.

In spite of the commonalities in upregulated genes when comparing baselines of progressing to non-progressing sites and progression, there were also specific signatures of the two comparisons.

On the other hand, breast (six patients, 12.2%) was the most common site of progression in the OED group, indicating that the patterns of progression may be different according to the number of extranodal organ.

The liver was the first site of progression in two patients: one with new lesions at 6.5 months and one with progression of existing liver lesions at 8.5 months after enrolment.

The rationale for this approach is that a substantial proportion of patients will progress within this timeframe while on chemotherapy and the site of progression is frequently in the liver or elsewhere outside of the conventional radiation field.

Large protein domain movements and remodeling of the active site orchestrate progression through the three chemical steps of the ligation reaction.

These systems exploit the labelling with conventional and novel integrin ligands for targeting the interface of cancer cells and of endothelial cells involved in cancer angiogenesis, with the proteins of the extracellular matrix, in the circulation, in tissues, and in tumour stroma, as the site of progression and metastatic evolution of the disease.