Sentence examples for site of the substrate from inspiring English sources

A charge reversal mutant at the putative anchor site of the substrate C terminus, R131E-R132E, dreducedlly reduced the proteolytic activity.

In this work, we applied computational and experimental methods to study the role of the P2 site and the P2′ site of the substrate peptide in the substrate cleavage of TACE.

These residuals are not only the binding site of glucose but the binding site of the substrate, so changes of the special residuals cause difference in degree of bond to glucose.

Further, we studied the participation of the cleavage site of the substrate in the species-specificity of hatching enzyme.

This example (along with many others) demonstrates the fact that the biological effects of sulfation can be determined by characterizing the sulfation site of the substrate.

Subsequently, a single substitution occurred within the cleavage site of the substrate, and the recent feature of species-specificity was established in the hatching enzyme-egg envelope system.

During the course of the molecular dynamics simulation, an average of 6.4 water molecules is observed in the camphor-binding site of the apo form, compared to zero water molecules in the binding site of the substrate-bound form, in agreement with the number of water molecules observed in crystal structures of the same species.

The cleavage site of the substrates is located in the middle of the two stems formed between the catalytic center.

HCV is suggested to replicate on the ER membrane, and therefore subcellular localization and distance of the cleavage site of the substrates from the membrane could be crucial for an efficient processing.

This is in perfect agreement with another study showing that the closed conformation is characterized by the TYR71 pointing to the active site of the substrate-bound complex.

The roles of organic counterions are discussed on the basis of probable solubilization sites of the substrate molecule in the gemini micelles, showing more growth in case of Sal− than Benz−.