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At the start of the examination, the patient is asked to point to the site of maximal tenderness.
The PC acquisition through the site of maximal stenosis can be used to measure the peak velocity (v) across the site of coarctation and the maximal pressure gradient across the coarctation (ΔP) can then be measured by use of the modified Bernoulli equation (ΔP = 4v2) [86].
Furthermore, we localized the site of maximal PPARβ/δ accumulation in the skin by immunohistochemistry.
Arterial pulse wave analysis was performed as follows: the radial artery was gently compressed with the tip of a tonometer at the site of maximal pulsation.
The 'Pz' electrode was the site of maximal statistical difference between fs-target and fs-distractor conditions, but the topography was clearly more posterior (Fig. 4 D) than that of the pre-saccade alpha (Fig. 4B); the ERP effects were similar in 'O1' and 'O2' (not shown).
Instead we suggest taking one biopsy from a site of maximal macroscopic inflammation.
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The following morphometric indexes were calculated by mean value of 5 consecutive cross sections of each identified lesion at the site of its maximal extent: maximal intimal thickness (IT), maximal intimal to media thickness ratio (IMT ratio), cross-sectional lesion area (LA), and lesion to intact wall area ratio (LA ratio).
We found a general trade-off between recruitment probability and dispersal distance; however, optimal recruitment sites were not necessarily associated to sites of maximal adult-plant density.
These results also indicate that optimal recruitment sites at a given time are not necessarily identical or even nearby sites of maximal adult-plant density, particularly in endozoochorously-dispersed plants (which is strongly directional).
Previous experimental studies with synthetic fragments and the 5S rDNA sequence from sea urchin have shown that the nucleosome positioning sequences TTAA and CTAG with the consensus YTAR are located at sites of maximal curvature in the nucleosome at positions +/−5, +/−15 +/−25 and +/−35 bp from the dyad [36] [38].
This suggests that there is a relationship between the quantitative delivery of the polymer-based prodrug and the severity of synovitis, with preferential localization of the prodrug at sites of maximal inflammation.
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