Herbivore-induced plant volatiles are released both locally, at the site of damage, and/or systemically in non-damaged leaves (Turlings and Tumlinson 1992; Halitschke et al. 2000).
Following tissue injury, fibroblasts migrate to the site of damage, where they deposit new collagen and facilitate the healing process.
"On the other hand, you want to place them as close to the site of damage as possible," he says.
Postreplication repair occurs downstream of the lesion, because replication is blocked at the actual site of damage.
XPC HR23B induces a bend in DNA upon binding and this is stabilized at the site of damage.
The transplanted cells, which are types of stem cells, migrate to the site of damage and release factors that ameliorate or may even replace dead tissues.
Nucleotide excision repair can also transpire in some organisms by a distinct biochemical mechanism involving only a single incision next to a site of damage (unimodal incision).
After epidermal wounding, tissue-bound cells around the wound site remain sessile and unresponsive, whereas circulating cells are rapidly recruited to the site of damage by adhesive capture.
The HSCs were administered locally at the site of damage in some studies or administered systemically through intravenous transplantation in other studies.
The repair of DSBs involves both posttranslational modification of nucleosomes and concentration of DNA-repair proteins at the site of damage.
These treatments may involve the use of biochemical techniques to induce tissue regeneration directly at the site of damage or the use of transplantation techniques employing differentiated cells or stem cells, either alone or as part of a bioartificial tissue.
