Sentence examples for site in the largest from inspiring English sources

Immediately surrounding the Metal A site in the largest subunit, the sequence NADFDGD is invariant among E. coli, chloroplast, archaeal (Pyrococcus), viral, and eukaryotic Pol I, II and III polymerases.

However, the D7N active-site mutant resolvase held the arms in a more planar arrangement in EDTA, Ca2+, or Mg2+ conditions, implicating metal-dependent contacts at the active site in the larger architecture of the complex.

Unlike colorectal tumours, methylation levels in the normal mucosa do not vary according to anatomical site in the large bowel.

The second major finding of this study was that promoter methylation levels in normal colonic mucosa showed no apparent associations with site in the large bowel.

Increasing their resistance or lowering the intensity of the caries challenge would lead to a substantial drop in cavitated sites providing the agent or agents offered sufficient protection for any single site in the larger groups.

These compounds bind within the more sequence-divergent transmembrane domains of the receptors, which are physically removed from the glutamate binding site in the large N-terminal domain of the Class C GPCRs.

Cas1 is a homodimeric enzyme with a two-domain structure and a canonical metal dependent nuclease active site in the large domain formed by a cluster of highly conserved residues (Wiedenheft et al., 2009).

Probably more typical, unfortunately, are the subjects who spent time in a drug testing site in Miami, the largest in the country until it was shut down for fire and safety violations.

The kinetics of appearance of sporozoites in these lymph nodes parallels that of the migration out of the inoculation site, in that the largest numbers of sporozoites appear in the lymph node 3 h after inoculation.

We propose that this catalyst had nearly saturated ion exchange positions in the 6-membered ring units (6MR) with copper ions, but still contained a significant amount of protonic sites in the large cages (8MR units).

Mapping of the binding site revealed a single region spanning transmembrane domains 9 12, which contrasts to the two binding sites in the large cytoplasmic domains in SV2A.