Sentence examples for site for modification from inspiring English sources

The disclosed results suggested that the C4′-position of aminoglycosides such as kanamycin may be an ideal site for modification to gain new modifying enzyme-resistant aminoglycoside antibiotics.

The p-Ac-Phe residue serves as a unique site for modification by hydroxamate-functionalized fluorescent dyes (Alexa 647, etc).

Since K/R99 is a potential site for modification, the inability to regulate by K/R99 via a reduction in variants that contain this site could be of importance.

Hyaluronic acid (HA) is widely used in the design of engineered hydrogels, due to its biofunctionality, as well as numerous sites for modification with reactive groups.

The most reactive sites for modification in human albumin are K190 and K351.

These sequentially remove potential sites for modification by phosphorylation (Fig. 2A).

We previously showed that truncated HTT (Httex1p) is SUMO-1 modified in cells and that Lys 6 (K6) and Lys 9 (K9) may represent primary sites for modification based on the absence of SUMO modification upon mutagenesis of target lysines (Steffan et al., 2004).

In contrast, the cytosolically localized T6ES3ES4E reporter was neither N-myristoylated or palmitoylated, demonstrating that this triple mutation that destroys three potential N-terminal phosphorylation sites also disrupts the acylation site required for modification at the N-terminus.

As a consequence of the oxygenase catalyzed activation, the new derivatives would likely also have a free hydroxyl group which would serve as a convenient site for further modification to help influence the absorption, metabolism, distribution, and excretion characteristic of the therapeutic compound.

Collectively, these experiments show that DRIL1 is sumoylated in vivo and that lysine 398 is the unique site for this modification.

Therefore, selecting a proper site for marker modification is critical for successfully constructing the marked viral infectious clone.