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Given that all of these patients had previously received chemotherapy, the side effects due to CIMAvax were minimal and limited to Grade 1 or 2 pain at the intramuscular injection site, fever, chills and headache.
According to the IOM report, the vaccine can create swelling and nodules at the injection site, fever and malaise, and in some people a period of "brief functional impairment".
During the initial clinical studies on healthy volunteers (who happened to be senior executives of the drug company), the drug caused extreme pain at the injection site, fever and abnormalities in blood chemistry that indicated inflammation.
The vast majority of these reactions to the HPV vaccine are not serious, consisting of pain at the injection site, fever, dizziness, and nausea.
In most cases, side effects are limited to pain at the injection site, fever, a mild rash or temporary swelling, according to the CDC.
Most adverse effects were local reactions at the injection site, fever and flu-like symptoms.
Similar(46)
At all sites fever clearance times were similar in artemether-lumefantrine-treated children (data not shown).
Similarly, at all sites fever clearance times were similar in artesunate-amodiaquine-treated children (data not shown).
Adverse effects that were possibly or probably related to the studied drug were grade 2 lymphopenia, anemia and neutropenia, local erythema at injection sites, fever and seizure.
Mild adverse reactions were reported in a small percentage of cases, including injection site reactions, fever, and rash.
Other side-effects include pain and swelling at the injection site, and fever; seizures can happen, but are rare.
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