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Generally, these pockets accommodate residue side chains from the peptide at the P1, P4, P6 and P9 positions with smaller pockets or shelves in the binding site accommodating the P3 and P7 residues; these pockets are numbered along the peptide relative to a large usually hydrophobic pocket near the peptide binding site.
The "front door" is the actual substrate-binding site accommodating the arginine side chain residue and derived inhibitors, while the "back door" provides solvent access through a highly polar tunnel connected to the base of the active site.
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The site accommodates 927 people at a time.
The Mazar-i-Sharif site accommodates about 1,400 trainees, General Patton said.
The site accommodates a number of British Army regimental museums, including those of the Parachute Regiment and the Royal Anglian Regiment.
As shown in Figure 7 figure supplement 1, this site accommodates ∼5 nt.
The active site accommodated the (6 S -HNE-1 S -HNE-1, N-dGuo adduct and itS -HNE-1plate dCyd neighbor.
In addition, helix-α2a and loop5 above the nucleotide-binding site, and helix-α0 below the nucleotide-binding site, accommodate Mg-ATP binding in both motors.
The nature of the basic sites accommodating colloid deposition is discussed based on X-ray photoelectron spectroscopy (XPS) results.
(B ) Sites accommodating beneficial mutations.
It has been pointed out that the polyspecificity/broad substrate specificity of ABC transporters due to multiple separate binding sites or "binding zones," binding sites accommodating more than one ligand and high protein flexibility determine a complex phenomenon which can only be partially addressed by current methods in the computational drug design field [ 23, 24].
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