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The twice-refocused diffusion encoding sequence, first described by Feinberg and Jacob [48], was incorporated into the M-EPI sequence by methods earlier reported using SIR alone [48], [49].
Globally, EVE was more efficient than SIR alone to decrease IL-8 and VEGF release from neutrophils.
In LPS-treated neutrophils, SIR alone did not reduce IL-8 release, whereas EVE partially inhibited IL-8 release from 65-fold to approximately 40-fold.
Finally, we report that in response to a pro-inflammatory stimulation (TNF-α), pre-treatment with TAC, EVE or SIR, alone or in combination, decreased the activation of the β2-integrin complex (CD11b/CD18), resulting in reduced neutrophil adhesiveness to HUVECs and hECM.
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However, to his disappointment, he did not receive the coveted office of King's Painter, which was held in the 1660s by Sir Peter Lely alone.
Of course, holding this rounded picture of the man only seems to be a problem for the people who want us to just leave poor old Sir John alone.
At the end Sir Alex Ferguson stood alone in the penalty box in front of the Smethwick End, raised both arms to the Manchester United supporters and took a bow.
It's time for you to leave these women alone, Sir".
The householders protested, and the Lord Mayor Sir Thomas Bloodworth, who alone had the authority to override their wishes, was summoned.
Pre-treatment with SIR and EVE, alone or in combination with CsA or TAC, significantly decreased the release of VEGF by neutrophils following all pro-inflammatory stimulations.
Sir Winston was not alone in this attitude to paying his bills.
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