Exact(1)
Studies on the activation of singular pathways by immunohistochemistry (IHC) with phosphorylation-specific antibodies have been reported for PKB/AKT [ 9, 10], p70/S6K [ 11], NFκB [ 12, 13] and STAT3 [ 14].
Similar(59)
These findings shift the view of the mesocorticolimbic system as a singular pathway for reward to a system with multiple signals across a wide range of domains that drive value-based decision making.
There is no singular pathway to extremism.
These findings suggest that both classes function in a singular pathway that is centered on Ctf7/Eco1 (herein termed Ctf7) regulation.
It seems particularly significant that the rbbA-yhjD double mutant increased the sensitivity of E. coli to antibiotics to a level comparable to that of the rbbA and yhjD single gene deletion strains, implying that these proteins may be part of a singular pathway.
This singular pathway is of great importance as it is the major pathway for supplying unpaired unstable electrons through the process of reduction.
Other studies such as verification of whether regulating a singular sensing pathway is more ideal or combining pathways will give an additive effect; and comparing the efficacy between established treatments and regulation of lipid-sensing system remained to be explored.
Collectively, our results indicate that the transduction of MPG-EGFP seems to utilize a less well-characterized endocytic pathway [ 23] and suggest that the transduction of MPG-EGFP is dependent on more than singular endocytic pathway, as amiloride and dynamin mutant are both able to reduce the transduction efficiency.
We identified a singular MLL-specific hypathwayvathatpathroughhAMPKhrough AMphosphorylationion leads to the activation of BCL-2, a well known anti-apoptotic regulator crucial for chemotherapy resistance already found to be over-expressed both at mRNA and protein levels in MLL-rearranged leukemias [18].
They are typically not the singular elements of important pathways but weak connectors among several pathways of high importance.
These data suggest that canonical Wnt signaling plays a role in OS progression and that while blockade of singular nodes in signaling pathways can have dramatic effects on individual cell lines, real tumors readily evade such focused attacks.
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