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In addition to functional single variations, functional haplotypes have also been reported within this locus.
The dataset contained 2156 single variations from ProTherm.
There were thirteen unique alterations identified, with 16 tumors having a single variations and four tumors having two separate variations (Table 3).
By applying these criteria, we initially identified a total of 19,980 SNPs and 1,174 INDELs distributed in 8,147 unigenes (16.4%), averaging a total of 2.6 single variations per unigene.
Other consensus DR2 elements containing one variation in the repeated motifs were much less frequent (less than 3,000 copies each for the single variations at the R and K positions, as calculated from the percentages in DR2 elements listed in Table 2).
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And those are just the fatalities that resulted from a single variation in one factor in one small state in one twenty-five-year period.
From this single variation it is clear that Moscheles, like Beethoven, saw the awkward yet intriguing touches in Diabelli's seemingly bumptious tune.
In 1819, Anton Diabelli, a Viennese music publisher, composed a little waltz and sent it to dozens of composers — he wanted each of them to write and send him a single variation, which he'd publish together in one volume.
This single variation is ancient enough to support the theory, to which I have long subscribed, that the earliest division among dogs was between large ones and small ones.
I've used a computer since 1989 and the established codes of layout have been in place since then with only a single variation in the font: Arial, double-spaced, justified.
Beethoven accepted the challenge, but rather than write a single variation on the theme he decided, instead, to write thirty-three, and to issue it as one work, which he didn't finish for four years — by which time he was also deep into the composition of his Ninth Symphony.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com