Sentence examples for single target gene from inspiring English sources

This first redundancy-based mechanism shows the limited changes in the overall pathway crosstalk based on a single target gene, which may explain the occurrence of resistance to targeted cancer therapy.

After phenotype evaluation of BC3F2 lines, NILs containing single target gene are obtained.

However, rather than probing a single target gene model, many of the oligos were designed to recognize more than one target transcript.

In most cases, their basic design allows the cloning of a single target gene, typically under a specific promoter, in parallel with the expression of selection and/or marker genes from the same vector.

Each move modifies a single target gene.

The problem is solved using dynamic programming in optimizing a downstream gene by turning on or off only a single target gene.

Although some single target genes directly regulated by HMGA2 have been identified there is little doubt that it rather acts as a global chromatin switch than as a transcription factor controlling a few genes only [4], [5], [6].

Compared to silencing of single target genes, SGS had a significant higher impact on apoptosis induction in pancreatic cancer cells.

Third, we focused our analysis on identified pathways suggested by microRNA targets, thereby minimizing the potential pitfall of placing too much emphasis on single target genes.

In addition, the analysis of single target genes in the endothelium certainly does not entirely reflect the complex setting of inflammation and coagulation in vivo.

We find that although the amount of information transmitted by Msn2 to single target genes is limited, information transduction can be increased by modulating promoter cis-elements or by integrating information from multiple genes.