Sentence examples for single specificity from inspiring English sources

One might therefore anticipate that joint inflammatory responses might be suppressed by arthritogenic antigen-specific Tregs of a single specificity even if autoreactivity to multiple auto-antigens were present.

The ability of antibody targeted HLA class I/peptide complexes to specifically induce the expansion of CTLs to a single specificity should prove useful for in vitro studies analysing the endogenous CTL response or the effects of other in vivo procedures.

The sixth proposition stated that "the immature antibody-forming cell is hypersensitive to an antigen antibody combination: it will be suppressed if it encounters the homologous antigen at this time", highlighting that each antibody-producing cell has a single specificity [17].

The ANA was positive along with one of the 12 specific autoantigens individually tested in 14 of the first positive serum from the 34 subjects with a single specificity.

Each T cell expresses thousands of T cell receptors (TCR) of a single specificity that allows inspection of peptide fragments bound by major histocompatibility complex molecules (MHC) on the surface of other cells.

Thus, the tests require (i) well-characterized transcription factor binding specificity and (ii) confident alignment of a binding site to a single specificity matrix.

However, this technique does not lend itself to histology and only single specificities can be analyzed.

As shown in Figure 4, the COGs in subfamilies I and V are corresponding to single specificities H3K9 (note that the amino acid context of H3K9 resembles that of K27, which likely leads to the dual-specificities of EHMT1 and EHMT2 [25]) and H3K4, respectively.

The single specificities that are able to initiate lupus autoimmunity include at least the autoimmune responses against 60 kD Ro, nRNP A, dsDNA, phospholipid, and ribosomal P. For lupus the initiating autoantogens do not generally include nRNP 70 K or Sm.

These data highlight that a major subset of AIM is characterized by the simultaneous presence of two or more autoantibodies rather than by single specificities.

Taken together, these data suggest that a major subset of AIM is characterized by complex associations of autoantibodies rather than by single specificities.