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"They ignored every single significant issue," Ms. Glaser said.
Only a single, significant QTL was detected in each experiment.
Only the current President Bush goes without receiving credit for a single significant accomplishment.
No single, significant drama defines their lives, only the whimsical vicissitudes of fate.
"Not a single significant country in the world supports this plan," he said.
A single significant lapse in this area can be your dominant impression of an entire meal.
We couldn't find a single significant high-tech company in an urban neighborhood.
What I can say is that every single significant counter-terrorism investigation depends hugely on communications data.
"We fared very well — not a single significant injury, not a single destroyed building or home".
Ireland simply failed to muster a single significant threat to the England line.
In those days, millions of copies of a single significant issue could be sold.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com