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While all of the cycling genes initially characterized were found to be targets or components of a single signalling pathway (the Notch signalling pathway), a second group of cyclic genes related to the Wnt signalling pathway was recently discovered in mice [4].
These top five pathways were then manually collated into a single signalling pathway that putatively underlies PRM-mediated cytoprotection.
In contrast to CML, the inhibition of a single signalling pathway will not usually be sufficient to overcome the proliferative advantage of the tumour.
A major event in the neoplastic transformation of thyroid follicular cells is the constitutive activation of a single signalling pathway, the RET/PTC - RAS - BRAF - MEK - ERK pathway.
It has become apparent that GPCR signalling events may be moulded by receptor dimerisation, or the formation of higher order oligomers and clusters within a single signalling complex.
We have defined a novel ECM-dependent mechanism that can explain the diverse developmental outcomes induced by a single signalling pathway.
Similar(54)
Participants are not simply out for a single signal change, she said.
But most televisions have only composite video (yellow-topped RCA cables), which creates what Mr. Eggers describes as video soup, with all the color channels mixed into a single signal.
On each firing, a single signal window is analyzed.
And output is single signal synthesized by CSS process.
Composite video uses a single signal to contain color, brightness and timing information.
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