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We then used the input MinION® reads with the SSPACE-LongRead [ 18] scaffolder to produce the final assembly, which is composed of a single scaffold.
That is due to level 0 being the root level which contains only a single scaffold, the root scaffold, that has exactly 102 children (distinct ring count scaffolds).
Target-focused libraries are often constructed around a single scaffold with one or more positions used to attach various chemical moieties or side chains.
Similarly, the polycationic nature of CS has limited successful combination with Fb into a single scaffold due to strong electrostatic interactions.
The blend of three different pharmacologically active moieties into a single scaffold resulted into synergistic effect in their bio-activity.
As identified by the terahertz pulsed imaging measurements, there is single scaffold area with the same concentration.
Herein, we have prepared eight "hybrid" hydrogel scaffolds in the form of continuous gradients such that a single scaffold contains spatially varied properties.
The synthetic methodology provides the potential to generate many hundreds of thousands of compounds based around a single scaffold or template.
Further, multiple model molecules were released from a single scaffold composite, demonstrating the capacity for multi-factor controlled release ideal for complex growth factor delivery from these structures.
The results demonstrated that high-affinity human antibodies can be generated from libraries with completely synthetic CDRs displayed on a single scaffold.
A facile method was then developed to integrate the low- and high-stiffness gelatin matrices into a single scaffold (S-scaffold) for pulpodentin complex regeneration.
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