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"A custodian engineer would watch every single repair and construction project from beginning to end".
Ward 8 doesn't have a single repair shop; residents must instead travel to co-ops in Northeast Washington or Alexandria.
The Kia Rio had the most expensive single repair as well as the highest total damage ($9,380) for all four repairs.
Biochemical analysis reveals a single repair enzyme-binding site on 9-1-1 that can be blocked competitively by the PCNA-binding cell-cycle regulator p21cip1/waf1.
Indiana sailed to Majuro Lagoon to be repaired enough to make the voyage back to Pearl Harbor; the resulting work was the largest single repair handled at Pearl Harbor other than the battleships damaged during the attack that started the war.
However, although detection of radiation induced foci is a useful tool to study DNA breaks formation and repair especially at low doses of IR, recent accumulating evidence suggest that γH2AX foci might also be induced by other DNA lesions than DSBs such as stalled replication forks [35] and even by stable association of single repair factors with chromatin in the absence of DNA damage [36].
Similar(40)
It is important to note that elevated expression of a single DNA repair protein is unlikely to result in enhanced DNA repair activity unless this protein plays a rate-limiting role in the repair pathway.
The fact that cells do not rely on a single DSB repair route, but instead have developed a complex network of redundant DSB repair mechanisms, underscores the risk of faulty DSB repair.
Lisby, M., Mortensen, U. H. & Rothstein, R. Colocalization of multiple DNA double-strand breaks at a single Rad52 repair centre.
The changes observed in man and their irreversibility with a single stage repair can be reproduced in sheep.
Our results suggest that common alterations in single DNA repair genes are not major determinants of lung cancer susceptibility among smokers.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com