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As a result, there is yet to be a single randomised clinical trial of either medications or psychotherapy for the treatment of sleep paralysis.
Treatments should generally not be chosen based only on evidence from observational studies or single randomised clinical trials.
Although the MEDLINE search produced 87 hits for melatonin, no single randomised, controlled clinical study was among them.
Although intraperitoneal mesh technique is the most popular repair method, various techniques were used in these 237 repairs without a single randomised trial.
This situation would be almost analogous to the hypothesis testing in a single randomised trial.
A single randomised controlled trial compared trimethoprim-sulfamethoxazole against vancomycin for staphylococcal infections.
38 39 One single randomised controlled trial that met our inclusion criteria examined children with sexual behavioural problems.
Moreover, findings from a single randomised controlled trial can be subject to substantial population bias which can skew results.
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The INTENT trial is a single-centre, single-blind, randomised controlled trial with outcomes assessment blinded to group allocations.
The study was designed as a single blind, randomised, dose-controlled trial.
Design Prospective, single blind, randomised clinical trial.
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