Sentence examples for single parent compound from inspiring English sources

Thus, dual inhibition of 5αR type 1 and type 2 can be achieved by applying a single parent compound.

We have relied on information from the biomonitoring report (CDC 2012), which indicates that the metabolites considered in this study have a single parent compound with one exception.

This can be an advantage in a health study if all the possible parent compounds are believed to act additively and with potency proportional to metabolite levels, but it can be a disadvantage if this is not the case or if the study is trying to characterize exposure to a single parent compound.

In order to protect the environment, future research should include not only direct effects of single parent compounds, but also indirect effects in the presence of other chemicals, including possible pesticide transformation products.

Robertson says there could be as many as 15 or 20 different metabolites of a single parent PCB compound, depending on how that compound is metabolized.

19 A recent pharmacokinetic study of single dose resveratrol confirmed that peak plasma concentrations of the parent compound following a single large 5 g ingestion reached only 539 ng/ml (2.4 μM).

In contrast, GU40C4, the parent compound, demonstrated single agent efficacy in the A673 Ewings' sarcoma xenograft model [ 12].

This, together with the observed higher exposure to the metabolite compared with the parent compound after single-dose administration indicates that the metabolite will contribute to a significant extent to the pharmacological activity of macitentan.

Compounding the situation further are single parent families where the guardian suffers from a MI or substance abuse, or families where both parents have a history of psychiatric disorders [ 14, 34].

Taking into account the large mass of the molecule (705 Da), a small impurity content which differs from the parent compound with more or less a single bond (C-H or C-O) cannot be noticed in the mixture spectrum.

The relative loss of parent compound and formation of metabolic products was determined using a single quadrupole LCMS instrument (Waters, Manchester, UK).