Sentence examples for single nucleotide changes from inspiring English sources

In addition to large chromosomal segmental changes, single nucleotide changes in the genome also make a substantial contribution to cancer progression.

A beacon probe was designed to detect one of the two documented single nucleotide changes in IS481 target allele of Bordetella holmesii genome as compared to Bordetella pertussis.

Intron six has ∼5770 bases with ∼190 single nucleotide changes.

In other words, indel events and single nucleotide changes are positively correlated.

These consisted of 11 single nucleotide changes, and one 1 bp duplication.

Multiple nucleotide changes are assumed to occur in the same order of time as single nucleotide changes do.

Using this system, we demonstrated that extracts from highly purified rat liver mitochondria possess the essential enzymatic activity to mediate precise single-nucleotide changes.

We previously demonstrated that extracts from highly purified rat liver mitochondria possess the essential enzymatic activity to mediate targeted single-nucleotide changes using chimeric ONs in vitro.

Site-specific single-nucleotide changes in chromosomal DNA of eukaryotic cells have been achieved using chimeric RNA/DNA oligonucleotides (ONs) and short single-stranded (SS) ONs.

In 5 of 10 such cases, this down expression was associated with germline single-nucleotide changes in the two recognition sequences in KIT for these miRNAs [22].

Chemically treated TILLING populations contain single-nucleotide changes in the genome.