Sentence examples for single normalization from inspiring English sources

We then normalized the data by dividing each profile by a single normalization factor, the median fold change across all compounds relative to a reference profile (a median of all profiles), as described by Dieterle et al. [ 76], and log-transformed them by log10 ni + x).

The PET raclopride binding template allows for direct computation of SCR parametric maps after a single normalization step.

One strategy to circumvent this issue is to limit recording to the early, non-exponential phase of the bleaching curve where the "bleaching" is less significant, and a single normalization basis may prove sufficient [8].

The effect of rc can now be incorporated into a single normalization constant badj = brc1.5, where it is assumed that an otherwise constant biological relationship is modified by an environmental variable rc that is included in the value of the normalization constant.

We ultimately used a linear model proposed by Potter et al.[ 18] which corrects for two sources of bias within a single normalization model.

If peptide ratios deviate from unity, for instance due to errors in sample loading, a single normalization factor, based on the sum, average or median of all peptide abundances, can be used to minimize this offset.

Both, the single molecule normalization (A,C) and the full data set normalization were applied (B,D).

There are other single channel normalization methods not considered here, such as normalization based on principle component analysis [45].

Binding orientation of the ligands of PDB entries 3MVJ (L A ), 3DNE (L B ), and 3DND (L C ). Compounds within the binding pocket were colored with the single molecule normalization, the compounds above with the full set normalization.

Hence, in the case of L C the single molecule normalization might be more robust than the full set normalization.

When the single molecule normalization is applied, one can not distinguish between a non-toxic and a detoxifying substructure because the normalization can only visualize differences within the structure.