It was a single-minded response from a driver who is focused on winning his first championship, despite his insistence he was not thinking about it.
Such is the genre's listless omnipresence, so well characterised by the phrase "landfill indie", that it is often counteracted with an equally single-minded response, an assertion tantamount to Pop: There Is No Alternative.
This sort of single-minded response has made some people rich over the years and allowed others to lead a worry-free retirement if they timed the markets right and died within a couple of decades.
These include transcriptional responses to environmental pollutants and low oxygen tension, mediated by the aryl hydrocarbon (Dioxin) receptor and hypoxia inducible factors (HIF), respectively, and controlling aspects of neural development, mediated by the single minded (SIM) proteins.
The Drosophila single minded transcription factor is a master developmental regulator (Nambu et al., 1991).
SIM2, the human orthologue of single minded, is expressed in the developing human brain (Rachidi et al., 2005).
An important and well-characterised master regulator of the adaptive response to alterations in oxygen tension is hypoxia-inducible factor (HIF), a transcriptional complex containing two (α and β) members of the basic-helix-loop-helix PAS (period-aryl hydrocarbon nuclear receptor translocator-single minded) family.
Had he come out on his own, Meek Mill would just be shouting, but under Mr. Ross's umbrella he's exulting, a logical response to the single-minded commitment to success his boss employs.
In response, the writer wonders whether this single-minded obsession with discovering at any cost the private sexual acts of the President doesn't deserve to be obstructed.
The one good exchange from that film is repeated in Zack Snyder's single-minded scare-tactic remake: when someone asks why the zombies congregate there, the response is: "Memory, maybe.
In response to questions about her sudden turnaround, Smith credited more sophisticated training techniques and a single-minded focus on swimming.
