Sentence examples for single gene examining from inspiring English sources

To this end we used PRIME models of individual breast cancer cell lines of the NCI-60 panel, and simulated via Minimization of Metabolic Adjustment (MOMA) (Segre et al., 2002) the knock down of all metabolic reactions catalyzed by a single gene, examining their effect on cell growth ('Materials and methods').

Using the rules generated by these single genes, we examined the test set.

As the phylogenies that included the new sequences were inferred from fragments of single genes, we examined only the most highly supported incongruences in detail.

Thirty-six ofthef the 116 single-copy genes examined had ω estimates along this branch equal to or greater than one, including all three CPF/CPFL genes.

The ability to selectively abolish expression of a single gene and to examine the resulting cellular phenotype has enabled substantial progress in the understanding of gene function.

To move beyond examining single gene effects on this development process, gene network analysis can be employed to identify groups (e.g. modules) of genes whose expression is regulated in a coordinated manner (gene network) [6], [7], [8].

However, our review of the current literature examining single gene analysis of mitochondrial diversity in sharks and rays (Additional file 4: Table S4) indicates that slow mutation rate alone cannot completely explain the low nucleotide diversity found in G. glyphis.

Our own identification of only five putative reciprocally lost homeologs in the grasses out of thousands of gene pairs and single copy syntenic genes examined is strikingly different.

A systems biology experimental approach was employed in the current study to expand upon the results of these previous experiments that examined single gene effects on the follicle assembly process.

The idea of focusing on single gene or SNP effects when examining a disease is derived from the very successful research over the past 30 years on Mendelian (single gene) disorders.

The Mikuls et al. study was hypothesis-driven, and the researchers examined a single gene × gene interaction [ 23].