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Single dose immunisation is a major goal in vaccine design.
43 Currently, the Indian national immunisation schedule's 9 months single dose immunisation coverage is 74%; 44 however, as this represents the average, coverage rates in some parts of the country may be even lower.
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Since 2012, the Centers for Disease Control and Prevention CDC Advisory Committeeee on Immunization Practice (ACIP) recommends immunisation with a single dose of 13-valent pneumococcal conjugate vaccine followed by a dose of PPV to all adults with immunocompromised conditions [ 11].
In summary, measurement of antibody response after immunisation with a single dose of pneumococcal conjugate vaccine using standard ELISA is a feasible method for estimating protection induced by vaccination.
The proportions of infants with a MenC rSBA titre ≥1 8 after immunisation with a single dose of Hib-MenC-TT at 12 months of age, without infant priming, reached up to 83%; a proportion that might be acceptable in countries where MenC disease is currently under control.
Administration of a single dose of MenC conjugate vaccine after infancy could be beneficial considering the already complex immunisation schedules with large numbers of vaccinations in the first year of life.
Prior to the introduction of the vaccine into the national immunisation programme, a catch-up vaccination campaign was initiated in which a single dose of the MenC conjugate vaccine was offered to all children aged from 14 months up to and including 18 years.
All study children were immunised according to the Expanded Programme of Immunisation guidelines [ 25], and children older than one year were de-wormed with a single dose of albendazole, provided that they had not been treated in the previous six months.
In March 2006, the American Academy of Paediatrics published their recommendation that adolescents 11 to 18 years of age should receive a single dose of acellular pertussis vaccines combined with diphtheria and tetanus toxoids (DTaP) instead of tetanus and diphtheria toxoids vaccine for booster immunisation.
Seventy-six millioneedildren need single dose treatment.
A pouch amounts to a single dose.
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