Sentence examples for single dose exposure from inspiring English sources

As a result, the difference in Cmax in single dose exposure between the generics is expected to be limited in actual clinical treatments.

Preliminary data investigating the effects of both DA and brevetoxin suggested that there are no synergistic effects of these toxins on mouse lethality following acute, single dose exposures (J. Naar, pers. comm).

The extremes in the NOEC values are reported for lentic studies that were primarily conducted as single dose exposures.

This response was accompanied by inversed baclofen effects from inhibition of cAMP formation after single dose exposures to stimulation of cAMP formation in cells pretreated for seven days.

To assess the effects of single dose exposures, cells were allowed to attach to the well surface for 24 hours and were then exposed for 4 hours to GABA (50 μM), nicotine (1 μM) or the combination of both agents.

In accord with these findings, single dose exposures of pancreatic cancer cells in vitro to GABA or baclofen also inhibited via this mechanism cell proliferation and migration induced by the beta-adrenergic receptor agonist isoproterenol [ 9].

Single-dose exposure to ZnONP produced the short-term lung inflammation via a MyD88-dependent TLR pathway.

However, an interesting finding was that upon single-dose exposure to carbapenem, the efflux pump system played a major role in bacterial survival compared with NDM-1.

The Y181C variant remained dominant as observed in studies of NVP-R following single-dose exposure in infants [12], [13] and in earlier studies of daily NVP monotherapy for treatment of infected individuals [35], [36].

In adult rats, a single-dose exposure significantly increased LH concentration in serum (Stoker et al. 2005).

In mice, radiation proctitis following 27 Gy single-dose exposure shows increased neutrophil numbers in the inflamed and fibrosed areas 2 and 14 weeks postirradiation.